Viability of Saccharomyces cerevisiae front Spirulina platensis

Abstract

Oxidative stress promotes intracellular changes that cause damage to the body leading to the development of various pathologies, and some sources of free radicals are present in our diet and also in medicines. The antioxidant compounds are used as defense mechanisms against free radicals and can be used in the food, cosmetics, beverages and pharmaceuticals industries. Spirulina platensis is a microalgae that has pigments (phycocyanin and carotenoids) and vitamins (ascorbic acid and tocopherol) responsible for its nutritional and therapeutic properties. In view of this, aimed at evaluating the antioxidant activity of Spirulina platensis front to damage caused by paracetamol, monosodium glutamate and by paraquat using as biological system cells of the yeast Saccharomyces cerevisiae. The antioxidant potential was evaluated using the method of cell survival. The results showed that the stress agents provoked high percentage of cell death. Spirulina platensis was able to raise significantly the survival of the yeast Saccharomyces cerevisiae when compared to treatments that received only the stress agents. The microalgae showed antioxidant capacity, protecting cells against damage caused by paracetamol, sodium monoglutamate and paraquat, proving to be as an alternative source for use as a nutritional supplement rich in antioxidant.