Sistemas adesivos universais – há 10 anos no Brasil: revisão de literatura
DOI:
https://doi.org/10.5335/rfo.v26i2.13257Palavras-chave:
Adesivos Dentinários, Esmalte Dental, DentinaResumo
Objetivo: analisar, a partir da literatura publicada, os sistemas adesivos universais, conceituando sobre seu
desempenho nos diferentes substratos, assim como potenciais estudos executados com eles após 10 anos no
Brasil. Materiais e métodos: para esta revisão narrativa, foram pesquisados artigos na língua inglesa nas bases
de dados eletrônicas PubMed/Medline, SciELO e Scopus, publicados de 2012 a 2022, período considerado
por ser a última década, além dos 10 anos da chegada do sistema adesivo universal ao Brasil. Utilizaram-se
os seguintes descritores: universal adhesives (adesivos universais) OR universal adhesive system (sistemas
adesivos universais). Realizou-se a inclusão de estudos laboratoriais (in vitro), ensaios clínicos, revisões de
literatura e sistemáticas com meta-análise. Resultados: após análise meticulosa, foram selecionados 56 estudos. Os adesivos universais são considerados mais “amigáveis” ao usuário, pois permitem ao clínico a
utilização no modo condicione e lave e autocondicionante, principalmente devido à inclusão do monômero
MDP ou de monômeros similares. No esmalte, o condicionamento ácido seletivo antes da aplicação do
adesivo é recomendado. Permite ser utilizado com uma diversidade de substratos, a aplicação de forma ativa
do adesivo melhora a resistência de união. Conclusão: os sistemas adesivos universais foram lançados para
tornar os procedimentos de adesão mais simples. Entretanto, mais ensaios clínicos com maiores tempos de
acompanhamento são necessários, para avaliar adequadamente a efetividade desse material.
Palavras-chave: adesivos dentinários; esmalte dental; dentina.
Downloads
Referências
Buonocore MG. A simple method of increasing the adhesion
of acrylic filling materials to enamel surfaces. J Dent Res
; 34(6):849-53. DOI: 10.1177/00220345550340060801.
Sofan E, Sofan A, Palaia G, Tenore G, Romeo U, Migliau G.
Classification review of dental adhesive systems: from the IV
generation to the universal type. Ann Stomatol 2017; 8(1):1-
DOI: 10.11138/ads/2017.8.1.001.
Van Landuyt KL, Snauwaert J, De Munck J, Peumans M,
Yoshida Y, Poitevin A, et al. Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials 2007; 28(26):3757-85. DOI: 10.1016/j.biomaterials.2007.04.044.
Giannini M, Soares CJ, De Carvalho RM. Ultimate tensile
strength of tooth structures. Dent Mater 2004; 20(4):322-9.
DOI: 10.1016/S0109-5641(03)00110-6.
Hanning M, Bock H, Bott B, Hot-Hanning W. Inter-crystallite nanoretention of self-etching adhesives at enamel imaged
by transmission electron microscopy. Eur J Oral Sci 2002;
(6):464-70. DOI: 10.1034/j.1600-0722.2002. 21326.x.
Perdigão J, Kose C, Mena-Serrano AP, De Paula EA, Tay LY,
Reis A, et al. A new universal simplified adhesive:18-month clinical evaluation, Oper Dent 2014; 39(2):113-27. DOI:
2341/13-045-C.
Meerbeek BV, De Munck J, Yoshida Y, Inoue S, Vargas M,
Vijay P, et al. Adhesion to enamel and dentin current status
and futures challenges. Oper Dent 2003; 28(3):215-35.
De Munck J, Van Landuyt K, Peumans M, Poitevin A, Lambrechts P, Braem M, et al. A critical review of the durability
of adhesion to tooth tissue: Methods and results. J Dent Res
; 84(2):118-32. DOI: 10.1177/154405910508400204.
Rosa WLO, Piva E, Silva AF. Bond strenght of universal
adhesives: A systematic review and meta-analysis. J Dent
; 43(7):765-76. DOI: 10.1016/j.jdent.2015.04.003.
Meda EM, Rached RN, Ignácio SA, Fornazari IA, Souza EM.
Effect of different adhesive strategies and time on microtensile bond strength of a CAD/CAM composite to dentin. Oper
Dent 2019; 44(6):262-72. DOI:10.2341/17-338-L.
Marchesi G, Frassetto A, Mazzoni A, Apolonio F, Diolosa
M, Cadenaro M, et al. (2014) Adhesive performance of a
multi-mode adhesive system: 1-year in vitro study. J Dent
(5):603-12. DOI: 10.1016/j.jdent.2013.12.008.
Zecin-Deren A, Sokolowski J, Szczesio-Wlodarczyk A, Piwonski I, Lukomska-Szymanska M, Lapinska B. Multi-layer application of self-etch and universal adhesives and the
effect on dentine bond strength. Molecules 2019; 24(2):345.
DOI: 10.3390/molecules24020345.
Perdigão J, Ceballos L, Giráldez I, Barraco B, Fuentes MV. Effect of a hydrophobic bonding resin on the 36-month performance of a universal adhesive-a randomized clinical trial. Clin Oral
Investig 2020; 24(2):765-76. DOI: 10.1007/s00784-019-02940-x.
Haak R, Hähnel M, Schneider H, Rosolowski M, Park KJ,
Ziebold D, et al. Clinical and OCT outcomes of a universal
adhesive in a randomized clinical trial after 12 months. J
Dent 2019; 90:103200. DOI: 10.1016/j.jdent.2019.103200.
Oz FD, Ergin E, Canatan S. Twenty-four-month clinical performance of different universal adhesives in etch-and-rinse,
selective etching and self-etch application modes in NCCL –
a randomized controlled clinical trial. J Appl Oral Sci 2019;
(27)90:103200. DOI: 10.1016/j.jdent.2019.103200.
Takeda M, Takamizawa T, Imai A, Suzuki T, Tsujimoto A, Barkmeier WW, et al. Immediate enamel bond strength of universal adhesives to ground surfaces in different etching modes.
Eur J Oral Sci 2019; 127(4):351-60. DOI: 10.1111/eos.12626.
Hardan L, Bourgi R, Kharouf N, Mancino D, Zarow M, Jakubowicz N, et al. Bond Strength of Universal Adhesives to
Dentin: A Systematic Review and Meta-Analysis. Polymers
(Basel) 2021; 13(5):814. DOI: 10.3390/polym13050814.
Loguercio AD, de Paula EA, Hass V, Luque-Martinez I, Reis
A, Perdigão J (2015) A new universal simplified adhesive:
-month randomized double-blind clinical trial. J Dent
(9):1083-1092. DOI: 10.1016/j.jdent.2015.07.005.
Mena-Serrano A, Kose C, De Paula EA, Tay LY, Reis A, Loguercio AD, Perdigão J (2013) A new universal simplified
adhesive: 6-month clinical evaluation. J Esthet Restor Dent
(1):55-69. DOI: 10.1111/jerd.12005.
Wagner A, Wendler M, Petschelt A, Belli R, Lohbauer U.
Bonding performance of universal adhesives in different
etching modes. J Dent 2014; 42(7):800-7. DOI: 10.1016/j.
jdent.2014.04.012.
Balkaya H, Arslan S, Pala K. A randomized, prospective clinical study evaluating effectiveness of a bulk-fill composite
resin, a conventional composite resin and a reinforced glass
ionomer in Class II cavities: one-year results J Appl Oral Sci
; 27. DOI: 10.1590/1678-7757-2018-0678.
Siqueira F, Cardenas AM, Gutierrez MF, Malaquias P, Hass
V, Reis A, et al. Laboratory performance of universal adhesive
system for luting CAD/CAM restorative materials. J Adhes
Dent 2016; 18(4):1-10. DOI: 10.1007/s00784-019-02940-x.
Muñoz MA, Luque-Martinez I, Hass V, Reis A, Bombarda
NHC. Imediate bonding properties of universal adhesives to dentine. J Dent 2013; 41(5):404-11. DOI: 10.1016/j.
jdent.2013.03.001.
Zanatta RF, Silva TM, Esper M, Bresciani E, Gonçalves S,
Canneppele P. Bonding Performance of Simplified Adhesive
Systems in Noncarious Cervical Lesions at 2-year Follow-up:
A Double-blind Randomized Clinical Trial. Oper Dent 2019;
(5):476-87. DOI: 10.2341/18-049-C.
Olegário IC, Hesse D, Bönecker M, Imparato JCP, Braga
MM, Mendes FM, et al. Effectiveness of conventional treatment using bulk-fill composite resin versus Atraumatic Restorative Treatments in primary and permanent dentition: a
pragmatic randomized clinical trial. BMC Oral Health 2017;
(1):34. DOI: 10.1186/s12903-016-0260-6.
Cardoso GC, Nakanishi L, Isolan CP, Jardim PS, Moraes RR.
Bond stability of universal adhesives applied to dentin using
etch-and-rinse or self-etch strategies. Braz Dent J 2019;
(5):467-75. DOI: 10.1590/0103-6440201902578.
Canali GD, Ignácio SA, Rached RN, Souza EM. One-year clinical evaluation of bulk-fill flowable vs. regular nanofilled
composite in non-carious cervical lesions. Clin Oral Investig
; 23(2):889-97. DOI: 10.1007/s00784-018-2509-8.
Rolim TZC, da Costa TRF, Wambier LM, Chibinski AC,
Wambier DS, Assunção LRS, et al. Adhesive restoration of
molars affected by molar incisor hypomineralization: a randomized clinical trial. Clin Oral Investig 2020; 25(3):1513-
DOI: 10.1007/s00784-020-03459-2.
Oz FD, Meral E, Ergin E, Gurgan S. One-year evaluation of
a new restorative glass ionomer cement for the restoration of
non-carious cervical lesions in patients with systemic diseases:
a randomized, clinical trial. J Appl Oral Sci 2020; 23:28:e. DOI:
1590/1678-7757-2020-0311.
Vogl V, Hiller KA, Buchalla W, Federlin M, Schmalz G. Controlled, prospective, randomized, clinical split-mouth evaluation of
partial ceramic crowns luted with a new, universal adhesive
system/resin cement: results after 18 months. Clin Oral Investig 2016; 20(9):2481-92. DOI: 10.1590/1678-7757-2020-0311.
Kosan E, Soares-Prates A, Blunck U, Neumann K, Bitter K.
Root canal pre-treatment and adhesive system affect bond
strength durability of fiber posts ex vivo. Clin Oral Investig
; 25(11):6419-34. DOI: 10.1007/s00784-021-03945-1.
Nowicka A, Lagocka R, Lipski M, Parafiniuk M, Grocholewicz K, Sobolewska E, et al. Clinical and histological evaluation of direct pulp capping on human pulp tissue using a dentin adhesive system. Biomed Res Int 2016; 2016:2591273.
DOI: 10.1155/2016/2591273.
Matos TP, Gutiérrez MF, Hanzen TA, Malaquias P, de Paula AM, de Souza JJ, et al. 18-month clinical evaluation of a
copper-containing universal adhesive in non-carious cervical
lesions: a double-blind, randomized controlled trial. J Dent
; 90:103219. DOI: 10.1016/j.jdent.2019.103219.
Vidal O, Matos TP, Nuñez A, Mendéz-Bauer L, Sutil E,
Ñaupari-Villasante R, et al. A universal adhesive containing copper nanoparticles improves the stability of hybrid
layer in a cariogenic oral environment: An in-situ study. J
Mech Behav Biomed Mater 2022; 126. DOI: 10.1016/j.jmbbm.2021.105017.
Sabatini C. Effect of a chlorhexidine-containing adhesive on
dentin bond strength stability. Oper Dent 2013; 38(6):609-
DOI: 10.2341/12-239-L.
Grasel R, Santos MJ, Rêgo HMC, Rippe MP, Valandro LF.
Effect of Resin Luting Systems and Alumina Particle Air
Abrasion on Bond Strength to Zirconia. Oper Dent 2018;
(3):282-90. DOI: 10.2341/15-352-L.
Perdigão J, Araújo E, Ramos RQ, Gomes G, Pizzolotto L. Adhesive Dentistry: Current concepts and clinical considerations. J
Esthet Restor Dent 2021; 33(1):51-68. DOI: 10.1111/jerd.12692.
De Melo LA, Moura IS, De Almeida EO, Freitas Junior AC,
Dias TGS, Leite FPP. Efficacy of prostheses bonding using
silane incorporated to universal adhesives or applied separately: a systematic review. J Indian Prosthodont Soc 2019;
(1):3-8. DOI: 10.4103/jips.jips_144_18.
Sezinando A, Luque-Martinez I, Muñoz MA, Reis A, Loguercio AD, Perdigão J. Influence of a hydrophobic resin coating
on the immediate and 6-month dentin bonding of three universal adhesives. Dent Mater 2015; 31(10):e236-246. DOI:
1016/j.dental.2015.07.002.
Moritake N, Takamiza T, Ishii R, Tsujimoto A, Barkmeier
WW, Latta MA, et al. Effect of active application on bond durability of universal adhesives. Oper Dent 2019; 44(2):188-
DOI: 10.2341/17-384-L.
Carrilho E, Cardoso M, Ferreira MM, Marto CM, Paula A,
Coelho AS. 10-MDP Based Dental Adhesives: Adhesive Interface Characterization and Adhesive Stability-A Systematic
Review. Materials 2019; 12(5):790. DOI: 10.2341/17-384-L.
Gutiérrez MF, Alegría-Acevedo LF, Nuñez A, Mendéz-Bauer
L, Ñaupari-Villasante R, de Souza JJ, et al. In vitro biological and adhesive properties of universal adhesive systems on
sound and caries- affected dentin: 18-months. Int J Adh Adh
; 114. DOI:10.1016/j.ijadhadh.2022.103107.
Awad MM, Alhalabi F, Alshehri A, Aljeaidi Z, Alrahlah A,
Özcan M, et al. Effect of Non-Thermal Atmospheric Plasma
on Micro-Tensile Bond Strength at Adhesive/Dentin Interface: a Systematic Review Materials (Basel) 2021; 14(4):1026.
DOI: 10.3390/ma14041026.
Costa C, Albuquerque NLG, Mendonça JS, Loguercio AD,
Saboia VPA, Santiago SL. Catechin-based Dentin Pretreatment and the Clinical Performance of a Universal Adhesive: a Two-year Randomized Clinical Trial. Oper Dent 2020;
(5):473-83. DOI: 10.2341/19-088-C.
Kucukyilmaz E, Celik EU, Ackay M, Yasa B. Influence of blood
contamination during multimode adhesive application on
the microtensile bond strength to dentin. Niger J Clin Pract
; (1):670-7. DOI: 10.4103/1119-3077.224127.
Nagarkar S, Theis-Mahon N, Perdigão J. Universal dental
adhesives: current status, laboratory testing, and clinical
performance. J Biomed Mater Res B Appl Biomater 2019;
(6):2121-31. DOI: 10.1002/jbm.b.34305.
Miletic V, Pongprueska P, De Munck J, Brooks NR, Meerbeek
BV. Monomer-to-polymer conversion and micro-tensile bond
strength to dentine of experimental and commercial adhesives containing diphenyl(2,4,6-trimethylbenzoyl) phosphine
oxide or a camphorquinone/amine photo-initiator system. J
Dent 2013; 41(10):918-26. DOI: 10.1016/j.jdent.2013.07.007.
Souza MY, Jurema ALB, Caneppele TMF, Bresciani E. Sixmonth performance of restorations produced with the ethanolwet-bonding technique: a randomized trial. Braz Oral Res 2019;
:e052. DOI: 10.1590/1807-3107bor-2019.vol33.0052.
Tardem C, Albuquerque EG, Lopes SL, Marins SM, Calazans FS, Poubel LA, et al. Clinical time and postoperative
sensitivity after use of bulk-fill (syringe and capsule) vs.
incremental filling composites: a randomized clinical trial.
Braz Oral Res 2019; 33(0):e089. DOI: 10.1590/1807-3107bor2019.vol33.0089.
Josic U, Maravic T, Mazzitelli C, Radovic I, Jacimovic J,
del Bianco F, et al. Is clinical behavior of composite restorations placed in non-carious cervical lesions influenced by
the application mode of universal adhesives? A systematic
review and meta-analysis. Dent Mater 2021; 37(11):503-21.
DOI: 10.1016/j.dental.2021.08.017.
Patil SA, Naik BD, Suma R. Evaluation of three different
agents for in-office treatment of dentinal hypersensitivity: a
controlled clinical study. Indian J Dent Res 2015; 26(1):38-
DOI: 10.4103/0970-9290.156796.
Loguercio AD, Luque-Martinez IV, Fuentes S, Reis A, Muñoz
MA. Effect of dentin roughness on the adhesive performance in non-carious cervical lesions: a double-blind randomized clinical trial. J Dent 2018; 69:60-9. DOI: 10.1016/j.
jdent.2017.09.011.
Seabra B, Arantes-Oliveira S, Portugal J. Influence of multimode universal adhesives and zirconia primer application techniques on zirconia repair. J Prosthet Dent 2014;
(2):182-7. DOI: 10.1016/j.prosdent.2013.10.008.
Luthra R, Kaur P. An insight into current concepts and techniques in resin bonding to high strength ceramics. Aust Dent
J 2016; 61(2):163-73. DOI: 10.1111/adj.12365.
de Souza G, Henning D, Aggarwal A, Tam LE. The use of
MDP-based materials for bonding to zirconia. J Prosthet
Dent 2014; 895-902. DOI: 10.1016/j.prosdent.2014.01.016.
Bömicke W, Schürz A, Krisam J, Rammelsberg P, Rues S.
Durability of resin-zirconia bonds produced using methods
available in dental practice. J Adhes Dent 2016; 18(1):17-27.
DOI: 10.1016/j.prosdent.2014.01.016.
Akturk E, Bektas OO, Ozkanoglu S, Akin EGG. Do ozonated water and boric acid affect the bond strength to dentin
in different adhesive systems? Niger J Clin Pract 2019;
(12):1758-64. DOI: 10.4103/njcp.njcp_281_19.
Lawson NC, Robles A, Fu CC, Lin CP, Sawlani K, Burgess
J. Two-year clinical trial of a universal adhesive in total-etch and self-etch mode in non-carious cervical lesions. J Dent
; 43(10):1229-34. DOI: 10.1016/j.jdent.2015.07.009.
Ruschel V, Shibata S, Stolf F, Chung Y, Baratieri L, Heymann
H, et al. Eighteen-month clinical study of universal adhesives
in noncarious cervical lesions. Oper Dent 2019; 43(3):241-9.
DOI: 10.2341/16-320-C.
Oz FD, Kutuk ZB, Ozturk C, Soleimani R, Gurgan S. An
-month clinical evaluation of three different universal
adhesives used with a universal flowable composite resin in
the restoration of non-carious cervical lesions. Clin Oral Investig 2019; 23(3):1443-52. DOI: 10.1007/s00784-018-2571-2.
Çakir NN, Demiburga S. The effect of five different universal adhesives on the clinical success of class I restoration:24-months clinical follow-up. Clin Oral Investig 2019;
(6):2767-76. DOI: 10.1007/s00784-018-2708-3.
Carvalho AA, Leite MM, Zago JKM, Nunes CABCM, Barata
TJE, Freitas GC, et al. Influence of different application protocols of universal adhesive system on the clinical behavior
of Class I and II restorations of composite resin – a randomized and double-blind controlled clinical trial. BMC Oral
Health 2019; 19(1):252. DOI: 10.1186/s12903-019-0913-3.
Downloads
Publicado
Edição
Seção
Licença

Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Este periódico bem como seus artigos estão licenciados com a licença Creative Commons Atribuição-NãoComercial-SemDerivações 4.0 Internacional.
