Association between apical periodontitis and diabetes mellitus: a literature review
DOI:
https://doi.org/10.5335/rfo.v24i1.8840Keywords:
Diabetes mellitus, Systemic disease, Endodontics, Periapical periodontitisAbstract
Objective: the present study aims to review the literature to verify the relationship between diabetes mellitus and apical periodontitis (AP). Literature Review: the AP is characterized by bone loss in the tooth apex region, mainly resulting from the contamination of the root canal system. Although AP is a local inflammatory process in the root periapex region, its development may be affected by systemic pathologies such as diabetes. Diabetes mellitus is a chronic condition that causes changes in insulin production or the resistance to its action, considering this hormone helps maintaining the normal concentration of blood glucose. The chronic hyperglycemia condition in decompensated diabetic patients causes physiological changes that allow establishing a relationship between diabetes and the development of the periapical lesions. Final considerations: the literature studied suggests a positive association between the presence of diabetes and the development of periapical lesions. However, although studies indicate a higher prevalence of apical periodontitis in diabetics, there is still little scientific evidence on the subject.
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