Salivary gland diseases: epidemiological study in a Stomatology service in southern Brazil

Authors

  • Victória Lopes Leal Pontifícia Universidade Católica do Rio Grande do Sul – PUCRS
  • Dieni da Silveira Teixeira Pontifícia Universidade Católica do Rio Grande do Sul – PUCRS
  • Maria Antonia Zancanaro de Figueiredo Pontifícia Universidade Católica do Rio Grande do Sul – PUCRS
  • Karen Cherubini Pontifícia Universidade Católica do Rio Grande do Sul – PUCRS
  • Fernanda Gonçalves Salum Pontifícia Universidade Católica do Rio Grande do Sul – PUCRS

DOI:

https://doi.org/10.5335/rfo.v24i2.10432

Keywords:

Epidemiology, Salivary glands, Mucocele, Oral neoplasms, Ranula, Sjögren’s Syndrome.

Abstract

Objective: to perform an epidemiological survey of salivary gland diseases by analyzing medical records from a Stomatology Service in southern Brazil. Methods: the sample consisted of approximately 24,000 medical records of patients assisted at the Stomatology Service of the São Lucas Hospital between 1977 and 2017. The following salivary gland disorders were selected: mucocele, ranula, sialolithiasis, infectious sialadenitis, Sjögren’s syndrome, necrotizing sialometaplasia, and benign or malignant neoplasms. The data collected were analyzed by descriptive and inferential statistics using the chi-squared test. Results: from the 817 disorders found, 56.2% were mucocele, 11.1% sialadenitis, 10.3% ranula, 10.1% sialolithiasis, 5.5% benign neoplasms, 4.3% Sjögren’s syndrome, 2.1% malignant neoplasms, and 0.4% necrotizing sialometaplasia. Mucocele was more prevalent in men, while ranula and Sjögren’s syndrome were more associated with women. The other diseases did not present gender preference. The location of the lesions, clinical characteristics, and age of the patients affected were also assessed. Conclusion: salivary gland diseases deserve special attention among stomatognathic system disorders due to the complex anatomy of such structures, the importance of saliva in the oral homeostasis, and the indolent clinical behavior of the malignant neoplasms affecting these glands.

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References

1. Pedersen AML, Sørensen CE, Proctor GB, Carpenter GH, Ekström J. Salivary secretion in health and disease. J Oral Rehabil 2018; 45(9):730-46.

2. Wilson KF, Meier JD, Ward PD. Salivary gland disorders. Am Fam Physician 2014; 89(11):882-8.

3. Mandel L. Salivary gland disorders. Med Clin North Am 2014; 98(6):1407-49.

4. Baurmash HD. Mucoceles and ranulas. J Oral Maxillofac Surg 2003; 61(3):369-78.

5. Delli K, Spijkervet FK, Vissink A. Salivary gland diseases: infections, sialolithiasis and mucoceles. Monogr Oral Sci 2014; 24:135-48.

6. Pollack CV Jr, Severance HW Jr. Sialolithiasis: case studies and review. J Emerg Med 1990; 8(5):561-5.

7. Schrøder SA, Andersson M, Wohlfahrt J, Wagner N, Bardow A, Homøe P. Incidence of sialolithiasis in Denmark: a nationwide population-based register study. Eur Arch Otorhinolaryngol 2017; 274(4):1975-81.

8. Abdel Razek AAK, Mukherji S. Imaging of sialadenitis. Neuroradiol J 2017; 30(3):205-15.

9. Epker BN. Obstructive and inflammatory diseases of the major salivary glands. Oral Surg Oral Med Oral Pathol 1972; 33(1):2-27.

10. Ienopoli S, Carsons SE. Extraglandular manifestations of primary Sjögren’s syndrome. Oral Maxillofac Surg Clin North Am 2014; 26(1):91-9.

11. Alamanos Y, Tsifetaki N, Voulgari PV, Venetsanopoulou AI, Siozos C, Drosos AA. Epidemiology of primary Sjögren’s syndrome in north-west Greece, 1982-2003. Rheumatology (Oxford) 2006; 45(2):187-91.

12. Lawal AO, Adisa AO, Kolude B, Adeyemi BF, Olajide MA. A review of 413 salivary gland tumours in the head and neck region. J Clin Exp Dent 2013; 5(5):e218-e22.

13. Sando Z, Fokouo JV, Mebada AO, Djomou F, NDjolo A, Oyono JL. Epidemiological and histopathological patterns of salivary gland tumors in Cameroon. Pan Afr Med J 2016; 23:66.

14. Vasconcelos AC, Nör F, Meurer L, Salvadori G, Souza LB, Vargas PA, et al. Clinicopathological analysis of salivary gland tumors over a 15-year period. Braz Oral Res 2016; 30.

15. Sarmento DJ, Morais ML, Costa AL, Silveira ÉJ. Minor intraoral salivary gland tumors: a clinical-pathological study. Einstein (Sao Paulo) 2016; 14(4):508-12.

16. Abrams AM, Melrose RJ, Howell FV. Necrotizing sialometaplasia. A disease simulating malignancy. Cancer 1973; 32(1):130-5.

17. More CB, Bhavsar K, Varma S, Tailor M. Oral mucocele: A clinical and histopathological study. J Oral Maxillofac Pathol 2014; 18(Suppl 1):S72-7.

18. Zhao YF, Jia Y, Chen XM, Zhang WF. Clinical review of 580 ranulas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98(3):281-7.

19. Re Cecconi D, Achilli A, Tarozzi M, Lodi G, Demarosi F, Sardella A, Carrassi A. Mucoceles of the oral cavity: a large case series (1994-2008) and a literature review. Med Oral Patol Oral Cir Bucal 2010; 15(4):e551-6.

20. Bezerra TM, Monteiro BV, Henriques ÁC, de Vasconcelos Carvalho M, Nonaka CF, da Costa Miguel MC. Epidemiological survey of mucus extravasation phenomenon at an oral pathology referral center during a 43 years period. Braz J Otorhinolaryngol 2016; 82(5):536-42.

21. Packiri S, Gurunathan D, Selvarasu K. Management of Paediatric Oral Ranula: a systematic review. J Clin Diagn Res 2017; 11(9):ZE06-ZE09.

22. Chi AC, Lambert PR 3rd, Richardson MS, Neville BW. Oral mucoceles: a clinicopathologic review of 1,824 cases, including unusual variants. J Oral Maxillofac Surg 2011; 69(4):1086-93.

23. Lustmann J, Regev E, Melamed Y. Sialolithiasis. A survey on 245 patients and a review of the literature. Int J Oral Maxillofac Surg 1990; 19(3):135-8.

24. Iro H, Zenk J, Escudier MP, Nahlieli O, Capaccio P, Katz P, et al. Outcome of minimally invasive management of salivary calculi in 4,691 patients. Laryngoscope 2009; 119(2):263-8.

25. Huoh KC, Eisele DW. Etiologic factors in sialolithiasis. Otolaryngol Head Neck Surg 2011; 145(6):935-9.

26. Crawford WH Jr, Guernsey LH. Sialolithiasis of minor salivary glands: report of case. J Oral Surg 1969; 27(8):649-52.

27. Brook I. The bacteriology of salivary gland infections. Oral Maxillofac Surg Clin North Am 2009; 21(3):269-74.

28. Fujibayashi T, Sugai S, Miyasaka N, Hayashi Y, Tsubota K. Revised Japanese criteria for Sjögren’s syndrome (1999): availability and validity. Mod Rheumatol 2004; 14(6):425-34.

29. Tsuboi H, Asashima H, Takai C, Hagiwara S, Hagiya C, Yokosawa M, et al. Primary and secondary surveys on epidemiology of Sjögren’s syndrome in Japan. Mod Rheumatol 2014; 24(3):464-70.

30. Juengsomjit R, Lapthanasupkul P, Poomsawat S, Larbcharoensub N. A clinicopathologic study of 1,047 cases of salivary gland tumors in Thailand. Quintessence Int 2015; 46(8):707-16.

31. Jaafari-Ashkavandi Z, Ashraf MJ, Moshaverinia M. Salivary gland tumors: a clinicopathologic study of 366 cases in southern Iran. Asian Pac J Cancer Prev 2013; 14(1):27-30.

32. Bradley PJ, McGurk M. Incidence of salivary gland neoplasms in a defined UK population. Br J Oral Maxillofac Surg 2013; 51(5):399-403.

33. Lukšić I, Virag M, Manojlović S, Macan D. Salivary gland tumours: 25 years of experience from a single institution in Croatia. J Craniomaxillofac Surg 2012; 40(3):e75-81.

34. Shen SY, Wang WH, Liang R, Pan GQ, Qian YM. Clinicopathologic analysis of 2736 salivary gland cases over a 11year period in South wes China. Acta Otolaryngol 2018; (14):1-4.

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Published

2019-12-17

Issue

Vol. 24 No. 2 (2019): RFO

Section

Investigação Científica

License

Licença Creative Commons
This work is licensed under aCreative Commons Atribuição-NãoComercial-SemDerivações 4.0 Internacional.

How to Cite

Salivary gland diseases: epidemiological study in a Stomatology service in southern Brazil. (2019). Revista Da Faculdade De Odontologia - UPF, 24(2), 176-182. https://doi.org/10.5335/rfo.v24i2.10432