Biocompatibility of titanium implants with and without hydroxyapatite coating

Abstract

The application of metallic implants has been demonstrated in comparative studies bya great number of authors. In this study, hydroxyapa ti te (RA) coating ti tani um fixtures and no HA coating titanium fixtures were implanted bilateral into the femur bone of albino rats to examine radiographic and histological aspects of the osseointegration. The experimental anirnals were sacrificed at fourth, twelfth and twenty fourth week where their femur bones were removed and x-ray examined. The specimens were placed in ten percent formaldehyde and slides were done for histological study. It was shown that HAcoatingimplants induce satisfactory osseointegration while no HA coating implants produced a poor osseointegration which was substituted by a fibrous connective tissue. Key words: osseointegration, implants, titanium, biocompatibility, hydroxyapatite.